WATER SOLUBLE VITAMINS
VITAMINS B9 & B12
Vitamins
|
Vitamin B9
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Vitamin B12
|
Other names
|
Folic acid, folacin, vitamin M, Fermentation
residue factor, anti-anaemic factor
|
Cyanocobalamin, extrinsic factor of Castle or
Animal Protein factor (APF)
|
Discovered by
|
Day et
al
|
Ricker
|
Daily requirement
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0.4 mg
|
1mg for adults
2-3 mg for children
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Sources
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Yeast, leafy vegetables, liver
Synthesized by colon bacteria
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Liver, red meat, milk, eggs (vegetables foods
are generally without B12)
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Functions
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Co-enzyme for the synthesis of proteins which
are essential for formation and maturation of RBCs.
Promotes synthesis of thymidilic acid and
DNA.
|
Formation and maturation of RBCs.
Formation of myelin sheath.
|
Deficiency
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Macrocytic (megaloblastic) anaemia.
Sprue (mouth ulceration in man).
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Pernicious anaemia.
Degeneration of spinal cord leading to ataxia
and paralysis.
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